Abstract Treatment of bacterial infections is one of the major challenges of our time due to the evolved resistance mechanisms of pathogens against antibiotics.To circumvent this problem, it is necessary to understand the mode of action of the drug and the mechanism of resistance of the pathogen.One of the most potent antibiotic targets is peptidog
Electric power grid liberalization is adapted worldwide with the intent to lower the electricity prices for end users.The market clearing procedure deployed by the operator can result in power flows which are incompatible with the transfer capacity of the grid, resulting in congestion.Redispatch, nodal and zonal pricing, and congestion management m
The rolling friction of a road bicycle tire was measured as Sundae Spoon a function of changing tire pressure.Five different tire pressures, ranging from 40 to 120 psi, were tested in increments of 20 psi.The power input to the pedals and wheel speed were collected using Sweeper a crank-based power meter and speed sensor.It was found that rolling f
Abstract Background There have been ongoing efforts to identify anti-tick vaccine targets to protect cattle from infestation with cattle fever ticks Rhipicephalus (Boophilus) microplus.Two commercial vaccines based on the tick gut protein Bm86 have had variable effectiveness, which has led to poor acceptance, and numerous studies have attempted to
Abstract The burst coding hypothesis posits that the occurrence of sudden high-frequency patterns of action potentials constitutes a salient syllable of the neural code.Many neurons, however, do not produce clearly demarcated bursts, an observation invoked to rule out the pervasiveness of this coding scheme across brain areas and cell types.Here we